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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2e99d37663d6150b8df5a51eb30a3692486d6d44bf4d2c58c690b47d1e5cd03' 
  AND token = 'ypQyc9lD9xBxjxBnUmGcXv7BNU8pauU60Z1H3r+ecCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}