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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64517cdaaac8d7c9ebddd829f36f4e913e9318760018ec946299ad5da5afb3a4' 
  AND token = '18YFuh5dD7aorHR68U7zlry+04Xbb5f6tY38Qa32NeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}