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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '62c18a118bf2aafd4c46c2a61a1ec1ddade6c2c12726f455b6358fe0ea243a3c' 
  AND token = 'XxxCHHq3MWUbH71bB2D+Q3oMc3GwP5+c2U3EPvYIyik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}