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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e827561ca81133aaf89025e38ed92b10e34487528d13a002e184c89adece64d7' 
  AND token = 'PYbbZleMqSahkjJMXKdL3KFiTLy2U6AQySlYGRt9Css=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}