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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f40158ac137ee1c83c2b5bbd41567cf432b97cb2bec46ff85897d012bbe8c5c' 
  AND token = 'rKzwkRA0Rb+c/tibWg4y0Il/uauDgnWbSUn7A8nnrKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}