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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8aaa5863771aa6bbb6309f12b24468fb0e394152d121bb78ce51463129b7dea1' 
  AND token = 'nVq6ToO4UGoP+VhoyUjxQQE+c8jWNuqevIqGbL/e/u4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}