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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04e608e4d1a4945891b612b8beb55762dd2ec5faf3e5604f6f0c28aac1df8593' 
  AND token = 'ZFweuE8rPANGyrRQYf7fICY/eRbcmAjtIVBHCL2JaMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}