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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de53e190f8397a603a5db3539515ca37b443735c8acb26b9fcc0ec8f58ea88d8' 
  AND token = 'sHLNy/XA9AjqrQARU0br3V061pmB2O7jfz3WW9AV0Aw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}