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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72a4db1390d58d9be41562e29982ff36af1167f21150fc528c214c1467855f95' 
  AND token = '84yrs59Xl9Lm6XL+Ow9JmMsfN+iPZKUu3aNvb84O0s8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}