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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b68efe2c20e12521a0da24f3a90592ef8573db603e8e4b45b6e24b023950122' 
  AND token = 'DCaIKgpSCMFTbFV71oNDHl2M/9004IpeNsN69wVGG58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}