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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75ca5f47751b1fca5c9a43477892c7de60a4d4bb96b977948d99e044d6358a2e' 
  AND token = 'OKfT+F6xC9wlemo0alr8nL371quY2cgLHQXfQkBi7as=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}