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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e561f5e04d2bfeeab27c19b6eb25c0cd47eef6c2fd0ef93cb0d95ad7b778878' 
  AND token = 'jFSHD5tH/LzAHzOIdycZoF6wY1Y/XkGHrMF0hUNrUGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}