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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '293afd256b320366bf366f2e35b6413ea32439ca9240afcc4515a59eeabb8cf2' 
  AND token = 'km7CL94uqPGX7MjzlS/v7p4l80fJ5uJUbjJLEMF9a2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}