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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cf5e2077b6bb1961c6e7baa5d22fc7f8cbda078d851afacb97f3dbabde92ce7' 
  AND token = 'S8eKdSzrHRx6l5wzhtb2aDWt16nF8wnT9Ci+NX6Lo5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}