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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18d082bb4c0e9b1261b612b8bb8feaaaa725829131b481551c3b0a13034ee65a' 
  AND token = 'z42hCjybpNR+EMb+mU4T6hePhlV8/Z5JkAkDkjNZrnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}