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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53ff279aab1c904bf88980f50ed03b876565c623fb314bbe2deb731a11e05b82' 
  AND token = 'g9B5Tz7OosjEj/qAV5SoF50MQPW/BtxNhZmajjEO/jo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}