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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f1282d195dacea750b84e2118bea60d5982c768c47a00b7389ddadb3a50ac50' 
  AND token = 'nef4IpehjeM8gsnVVOkugXuiJV+X7o3ZvaTTyepP1iQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}