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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fa415468a685d9d4f9d00d525ffa6177d134b26e1dadbe09fe36d06fb2f3a87' 
  AND token = 'Szp5qs1bQH8jtRc8eqqN1jDgRjYGIeCXHx8OO+VJAYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}