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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0151877fd1fb85d7c1efb05283202cf8e76d1bdbe7d84f7649cda6ead883212d' 
  AND token = 'B1qy7zTjkQYCpz+Ulv2605KSdacDYw0hmDNjR+2hXyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}