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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43ef2bd376a0995d9cdbd4a37dd5bbc06bf1f6b15ebec6074dc7acce0b337073' 
  AND token = 'tFcp6oI6fC/8K4/zjvVSJkwPNZ/tCfnjmSJj10Cnj4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}