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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e08285487587f65140277e3e50e3cf24cd7dbbabe36d2e47f5594646e8d362e7' 
  AND token = 'DRv/RdVKb9hm9Udpm0E4jpM58Hhc1FCEXu1hJa7iSuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}