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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '650da06931b090105faca29d43b8aa70fd0e5e5d758b5038ef7beb07b34e9a53' 
  AND token = 'CqWm/bHR3Yc0Cde2hTkLzd+oo+dXDq65FFDOL2hiIQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}