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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6e07a6124048f13787d01df31a1b7f9883c1d29b165882604f9ce6e55894b77' 
  AND token = '8ESUUUXoKPKTEtFONtmSgpowohse6LAjTiZnyS2IEdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}