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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e69a4aea8d70823a66d2bda28d673f9aa0ca55883a4cb92033be0a95d055851' 
  AND token = 'lxMsDj8xF/PGqFQbNx2fDPZXwsKno9kwIsSNfGY7lPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}