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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9b94e81849549249e703379935bd10db19622eeb52812be0aecf67fbb3b089d' 
  AND token = 'cI3R6aT40vIsvvFUU4zcmV1G/G+FeyDR16kIGIx9yus=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}