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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '784d0bd1bdf7254d6a0471f1b40660f6dd4f3c881245fe97520d46d8180bc25b' 
  AND token = 'EUM/6B0Kuzm9f+90nvOV4y43SlKNiutRcDP2d1r3rlk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}