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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74c4e244648185c93efa523300a521827bfa630fe6f9b01352f1202d5263bf45' 
  AND token = 'q/eSSMHanNiBVk5z5B/XMlyZ4HAG1nqCGgdQaGL9q40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}