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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb61deabcd4ab80138c43636cf022d48c5c887b6719e503057e04f6267442243' 
  AND token = 'EFF/+Sr3TKjywGZ8Hs0lXRIb47hp3d0X2NQ027lNH9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}