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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cca8dce1729b4ae2590f12068de8b556a2af91474e8bf6b2fce8398618da10e' 
  AND token = 'LGyM8rUkUI5P60MIIsqKb81IWK3dN8ZtYOmXIWYUgNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}