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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53bdebe396bf0983ef36fd1612289a5d7fe76f4ca4ec38e88b05797887493ca8' 
  AND token = 'Ody40SLaEZ7EW9i1m5uH4+Cech49nKYYvCm+oo8XC9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}