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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce43e1b13a3bc0e2325e61bd5a67cb439411da61d0f8a1886187e92073a09694' 
  AND token = 'IQpBbQbw/KO44TltxvzMcbFEGGOl6ma/hxbebrejPOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}