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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fc5c71c39afe2cdf5244b669319f3f408f2d3dfaa113c6e2a91c431fd170082' 
  AND token = 'EXsiYT6SFPwEKtbPiM52D8DR7gMHNfTp+6YmEQI0xS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}