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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '92425f69d0800296f73437cd1431c2b3f05aa4963234b58f72ec925416e5acc6' 
  AND token = 'nGri0t+Vrqos3eqgQ1eoB8G52dQ9dYpPcgbGLQaWAco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}