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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7845b6662f1652e2685296f8f4b25822cd46c811c9309a221337a27f23f2a44b' 
  AND token = 'vfNgjpwKWPWqZP2bIDSBWg6Fy16rMuBuTlxpdr1Ji9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}