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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0aee52b1a2825e821385432025678f63f0329b99511f8e73254c2898d1bd5a7e' 
  AND token = '5h/z90pUBm7fohTboji1NIGijc/+R7O3lfryrp9zDrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}