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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6db0e96210d5908735e185439224db66249ac60e354dfa73704f248d3c7c693d' 
  AND token = 'Ky7A8s7sQ3nsT2pBTEC+rS81oVgPSeRCed0YeraMfJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}