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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37eb083addd7ddd68be9d4ddffd43d7a60a573c5fbd7c6b932f6f4bbb6d439a9' 
  AND token = 'mPjbs/P2T4vIhnAdk1VqdgCH8QpWXBO2MHgde4c1KqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}