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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '091a03dd26b0463e99dbbb3945d3b1431d5eaaa7dd989e05cc95ea2d2b5649da' 
  AND token = 'DDl8ll87/4v1Htsd1y+YdiVodv0AKrS7NbbqgybsfpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}