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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac4a66b0a2a2c841937e4ff6bdec37e66038636c6f29270c2e87735d4ff7a92e' 
  AND token = '353GJaHf4gQBp94yPtEhGq06qqLYDSzXqmti3uej9q4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}