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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecda1c4dcadb3bf28d0426ae2d879a774ba6d5f972e059d8d9583d67222ac3c4' 
  AND token = 'jpx78esWe6h2uR3bqIUATV9q744SuY08Xeftmh8s+LU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}