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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a59ca6bff6b445be5b653b1cc9c74cab9b890331904c8123d881f2f195bbc8a6' 
  AND token = 'eE844UhCLpPTAaw73l1z3N2NTXDBB7IASdU22AObK58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}