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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fad90fee6a53c8f13a38701d6a78460217d820ec7e3fa9919ffc15beafb9af50' 
  AND token = '+N1TTe5HrEUGHuPRw2g5tT4VMQROOmuFVYb0U90LyVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}