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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65f6a7aa49c43746b6e13235cdbde8d6cb71618a76b456c512d51e74529bbd4b' 
  AND token = '5R2uAMc8mNvzQ5nubjJvMRA93Iiw9dRh3E/Xsj0YaHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}