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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a5cb514311bed352594b5ffa9820c75944afc92c41fb0418a6a493712d597b2' 
  AND token = 'J6FN+CWoL9m2z1hrI0pIdEHhN63IBz4KuzfUY2lIlR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}