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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f1ef37e8fbf92dce46bd7b78efd7156edf0bcbfaeb761bfcd44c438eb293502' 
  AND token = 'fUk8+0UbXgbhifuPO5mysXff+vmx0LrnMav25jyaAUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}