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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aac57d25553a46d6f7de1767c1fadc3d61a2b0ff6062d9116d0de465436c6cdc' 
  AND token = 'Y3oMMrXlu6WTc/GD5JUwhleYy2hE0jwnCOTmKKP4IMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}