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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '242f026912c36a47652fbdc09a5a9b9fa7b6b9c84c2718d8c0ed34c3e899b164' 
  AND token = '5o70fOsmlWVLT7q97FxghnHbdX1aPN5oDsfMHyuo4cc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}