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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7287bc9373b542c0ce932bd376679d3fca89ebd1d4f613e866394d44425f7178' 
  AND token = 'Rc5zjyESvR37RJ0mj6MccoDLe/8H9PcAJ5Z9S0NImgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}