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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e22b4703ad42d5f9397cd4c88ca919e2bc3d78ef2c8335524925adc7a1c712d5' 
  AND token = 'eShJSPSNatOoQeFVjLK8o7o+24oFhiC+SSbGlUVIYS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}