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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5ae8ab68eb4a853ba01232dbe871e42d42a01c17165a8524070a4e2c19a5144' 
  AND token = 'y1c+RWUGudRO1Aj2dptOMnj+vOjaXoffAk/3sSk2iEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}